Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial.
Identifieur interne : 000969 ( Main/Exploration ); précédent : 000968; suivant : 000970Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial.
Auteurs : Jorge A. Bezerra [États-Unis] ; Cathie Spino ; John C. Magee ; Benjamin L. Shneider [États-Unis] ; Philip Rosenthal [États-Unis] ; Kasper S. Wang [États-Unis] ; Jessi Erlichman [États-Unis] ; Barbara Haber [États-Unis] ; Paula M. Hertel [États-Unis] ; Saul J. Karpen [Géorgie (pays)] ; Nanda Kerkar [États-Unis] ; Kathleen M. Loomes [États-Unis] ; Jean P. Molleston ; Karen F. Murray [États-Unis] ; Rene Romero [Géorgie (pays)] ; Kathleen B. Schwarz [États-Unis] ; Ross Shepherd [États-Unis] ; Frederick J. Suchy ; Yumirle P. Turmelle [États-Unis] ; Peter F. Whitington [États-Unis] ; Jeffrey Moore ; Averell H. Sherker [États-Unis] ; Patricia R. Robuck [États-Unis] ; Ronald J. SokolSource :
- JAMA [ 1538-3598 ] ; 2014.
Descripteurs français
- KwdFr :
- Administration par voie orale, Analyse de survie, Atrésie des voies biliaires (), Atrésie des voies biliaires (traitement médicamenteux), Bilirubine (sang), Drainage (), Femelle, Hormones corticosurrénaliennes (administration et posologie), Hormones corticosurrénaliennes (effets indésirables), Humains, Hépato-porto-entérostomie, Mâle, Méthode en double aveugle, Méthylprednisolone (administration et posologie), Méthylprednisolone (effets indésirables), Nourrisson, Perfusions veineuses, Prednisolone (administration et posologie), Prednisolone (effets indésirables), Résultat thérapeutique.
- MESH :
- administration et posologie : Hormones corticosurrénaliennes, Méthylprednisolone, Prednisolone.
- effets indésirables : Hormones corticosurrénaliennes, Méthylprednisolone, Prednisolone.
- sang : Bilirubine.
- traitement médicamenteux : Atrésie des voies biliaires.
- Administration par voie orale, Analyse de survie, Atrésie des voies biliaires, Drainage, Femelle, Humains, Hépato-porto-entérostomie, Mâle, Méthode en double aveugle, Nourrisson, Perfusions veineuses, Résultat thérapeutique.
English descriptors
- KwdEn :
- Administration, Oral, Adrenal Cortex Hormones (administration & dosage), Adrenal Cortex Hormones (adverse effects), Biliary Atresia (drug therapy), Biliary Atresia (surgery), Bilirubin (blood), Double-Blind Method, Drainage (methods), Female, Humans, Infant, Infusions, Intravenous, Male, Methylprednisolone (administration & dosage), Methylprednisolone (adverse effects), Portoenterostomy, Hepatic, Prednisolone (administration & dosage), Prednisolone (adverse effects), Survival Analysis, Treatment Outcome.
- MESH :
- chemical , administration & dosage : Adrenal Cortex Hormones, Methylprednisolone, Prednisolone.
- chemical , adverse effects : Adrenal Cortex Hormones, Methylprednisolone, Prednisolone.
- chemical , blood : Bilirubin.
- drug therapy : Biliary Atresia.
- methods : Drainage.
- surgery : Biliary Atresia.
- Administration, Oral, Double-Blind Method, Female, Humans, Infant, Infusions, Intravenous, Male, Portoenterostomy, Hepatic, Survival Analysis, Treatment Outcome.
Abstract
Biliary atresia is the most common cause of end-stage liver disease in children. Controversy exists as to whether use of steroids after hepatoportoenterostomy improves clinical outcome.
DOI: 10.1001/jama.2014.2623
PubMed: 24794368
Affiliations:
- Géorgie (pays), États-Unis
- Californie, Illinois, Maryland, Missouri (État), Ohio, Pennsylvanie, Texas, Washington (État)
- Houston, Los Angeles
Links toward previous steps (curation, corpus...)
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Le document en format XML
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Schwarz</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Shepherd, Ross" sort="Shepherd, Ross" uniqKey="Shepherd R" first="Ross" last="Shepherd">Ross Shepherd</name><affiliation wicri:level="3"><nlm:affiliation>Baylor College of Medicine and Texas Children's Hospital, Houston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>Baylor College of Medicine and Texas Children's Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Suchy, Frederick J" sort="Suchy, Frederick J" uniqKey="Suchy F" first="Frederick J" last="Suchy">Frederick J. Suchy</name><affiliation><nlm:affiliation>University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.</nlm:affiliation><wicri:noCountry code="subField">Aurora</wicri:noCountry></affiliation></author><author><name sortKey="Turmelle, Yumirle P" sort="Turmelle, Yumirle P" uniqKey="Turmelle Y" first="Yumirle P" last="Turmelle">Yumirle P. Turmelle</name><affiliation wicri:level="2"><nlm:affiliation>Washington University School of Medicine, St Louis, Missouri.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Washington University School of Medicine, St Louis</wicri:cityArea></affiliation></author><author><name sortKey="Whitington, Peter F" sort="Whitington, Peter F" uniqKey="Whitington P" first="Peter F" last="Whitington">Peter F. Whitington</name><affiliation wicri:level="2"><nlm:affiliation>Lurie Children's Hospital of Chicago, Chicago, Illinois.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Lurie Children's Hospital of Chicago, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Moore, Jeffrey" sort="Moore, Jeffrey" uniqKey="Moore J" first="Jeffrey" last="Moore">Jeffrey Moore</name><affiliation><nlm:affiliation>University of Michigan, Ann Arbor.</nlm:affiliation><wicri:noCountry code="subField">Ann Arbor</wicri:noCountry></affiliation></author><author><name sortKey="Sherker, Averell H" sort="Sherker, Averell H" uniqKey="Sherker A" first="Averell H" last="Sherker">Averell H. Sherker</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Robuck, Patricia R" sort="Robuck, Patricia R" uniqKey="Robuck P" first="Patricia R" last="Robuck">Patricia R. Robuck</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Sokol, Ronald J" sort="Sokol, Ronald J" uniqKey="Sokol R" first="Ronald J" last="Sokol">Ronald J. Sokol</name><affiliation><nlm:affiliation>University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.</nlm:affiliation><wicri:noCountry code="subField">Aurora</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24794368</idno><idno type="pmid">24794368</idno><idno type="doi">10.1001/jama.2014.2623</idno><idno type="wicri:Area/PubMed/Corpus">002D35</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002D35</idno><idno type="wicri:Area/PubMed/Curation">002D16</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002D16</idno><idno type="wicri:Area/PubMed/Checkpoint">002D16</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002D16</idno><idno type="wicri:Area/Ncbi/Merge">001E40</idno><idno type="wicri:Area/Ncbi/Curation">001E40</idno><idno type="wicri:Area/Ncbi/Checkpoint">001E40</idno><idno type="wicri:Area/Main/Merge">000974</idno><idno type="wicri:Area/Main/Curation">000969</idno><idno type="wicri:Area/Main/Exploration">000969</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial.</title><author><name sortKey="Bezerra, Jorge A" sort="Bezerra, Jorge A" uniqKey="Bezerra J" first="Jorge A" last="Bezerra">Jorge A. Bezerra</name><affiliation wicri:level="2"><nlm:affiliation>Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Cincinnati Children's Hospital Medical Center, Cincinnati</wicri:cityArea></affiliation></author><author><name sortKey="Spino, Cathie" sort="Spino, Cathie" uniqKey="Spino C" first="Cathie" last="Spino">Cathie Spino</name><affiliation><nlm:affiliation>University of Michigan, Ann Arbor.</nlm:affiliation><wicri:noCountry code="subField">Ann Arbor</wicri:noCountry></affiliation></author><author><name sortKey="Magee, John C" sort="Magee, John C" uniqKey="Magee J" first="John C" last="Magee">John C. Magee</name><affiliation><nlm:affiliation>University of Michigan, Ann Arbor.</nlm:affiliation><wicri:noCountry code="subField">Ann Arbor</wicri:noCountry></affiliation></author><author><name sortKey="Shneider, Benjamin L" sort="Shneider, Benjamin L" uniqKey="Shneider B" first="Benjamin L" last="Shneider">Benjamin L. Shneider</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Children's Hospital of Pittsburgh of UPMC, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Rosenthal, Philip" sort="Rosenthal, Philip" uniqKey="Rosenthal P" first="Philip" last="Rosenthal">Philip Rosenthal</name><affiliation wicri:level="2"><nlm:affiliation>UCSF Benioff Children's Hospital, San Francisco, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>UCSF Benioff Children's Hospital, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Kasper S" sort="Wang, Kasper S" uniqKey="Wang K" first="Kasper S" last="Wang">Kasper S. Wang</name><affiliation wicri:level="3"><nlm:affiliation>Children's Hospital Los Angeles and University of Southern California, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Children's Hospital Los Angeles and University of Southern California</wicri:orgArea></affiliation></author><author><name sortKey="Erlichman, Jessi" sort="Erlichman, Jessi" uniqKey="Erlichman J" first="Jessi" last="Erlichman">Jessi Erlichman</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Children's Hospital of Philadelphia, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Haber, Barbara" sort="Haber, Barbara" uniqKey="Haber B" first="Barbara" last="Haber">Barbara Haber</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of Philadelphia, Philadelphia, Pennsylvania17Dr Haber is now with Merck Research Laboratories, Upper Gwynedd, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Children's Hospital of Philadelphia, Philadelphia, Pennsylvania17Dr Haber is now with Merck Research Laboratories, Upper Gwynedd</wicri:cityArea></affiliation></author><author><name sortKey="Hertel, Paula M" sort="Hertel, Paula M" uniqKey="Hertel P" first="Paula M" last="Hertel">Paula M. Hertel</name><affiliation wicri:level="3"><nlm:affiliation>Baylor College of Medicine and Texas Children's Hospital, Houston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>Baylor College of Medicine and Texas Children's Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Karpen, Saul J" sort="Karpen, Saul J" uniqKey="Karpen S" first="Saul J" last="Karpen">Saul J. Karpen</name><affiliation wicri:level="1"><nlm:affiliation>Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.</nlm:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Kerkar, Nanda" sort="Kerkar, Nanda" uniqKey="Kerkar N" first="Nanda" last="Kerkar">Nanda Kerkar</name><affiliation wicri:level="3"><nlm:affiliation>Mount Sinai School of Medicine, New York, New York18Dr Kerkar is now with Children's Hospital Los Angeles and University of Southern California, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Mount Sinai School of Medicine, New York, New York18Dr Kerkar is now with Children's Hospital Los Angeles and University of Southern California</wicri:orgArea></affiliation></author><author><name sortKey="Loomes, Kathleen M" sort="Loomes, Kathleen M" uniqKey="Loomes K" first="Kathleen M" last="Loomes">Kathleen M. Loomes</name><affiliation wicri:level="2"><nlm:affiliation>Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Children's Hospital of Philadelphia, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Molleston, Jean P" sort="Molleston, Jean P" uniqKey="Molleston J" first="Jean P" last="Molleston">Jean P. Molleston</name><affiliation><nlm:affiliation>Indiana University School of Medicine and Riley Hospital for Children, Indianapolis.</nlm:affiliation><wicri:noCountry code="subField">Indianapolis</wicri:noCountry></affiliation></author><author><name sortKey="Murray, Karen F" sort="Murray, Karen F" uniqKey="Murray K" first="Karen F" last="Murray">Karen F. Murray</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Children's Hospital, Seattle, Washington.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Seattle Children's Hospital, Seattle</wicri:cityArea></affiliation></author><author><name sortKey="Romero, Rene" sort="Romero, Rene" uniqKey="Romero R" first="Rene" last="Romero">Rene Romero</name><affiliation wicri:level="1"><nlm:affiliation>Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.</nlm:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Schwarz, Kathleen B" sort="Schwarz, Kathleen B" uniqKey="Schwarz K" first="Kathleen B" last="Schwarz">Kathleen B. Schwarz</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins University School of Medicine, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Shepherd, Ross" sort="Shepherd, Ross" uniqKey="Shepherd R" first="Ross" last="Shepherd">Ross Shepherd</name><affiliation wicri:level="3"><nlm:affiliation>Baylor College of Medicine and Texas Children's Hospital, Houston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>Baylor College of Medicine and Texas Children's Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Suchy, Frederick J" sort="Suchy, Frederick J" uniqKey="Suchy F" first="Frederick J" last="Suchy">Frederick J. Suchy</name><affiliation><nlm:affiliation>University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.</nlm:affiliation><wicri:noCountry code="subField">Aurora</wicri:noCountry></affiliation></author><author><name sortKey="Turmelle, Yumirle P" sort="Turmelle, Yumirle P" uniqKey="Turmelle Y" first="Yumirle P" last="Turmelle">Yumirle P. Turmelle</name><affiliation wicri:level="2"><nlm:affiliation>Washington University School of Medicine, St Louis, Missouri.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Washington University School of Medicine, St Louis</wicri:cityArea></affiliation></author><author><name sortKey="Whitington, Peter F" sort="Whitington, Peter F" uniqKey="Whitington P" first="Peter F" last="Whitington">Peter F. Whitington</name><affiliation wicri:level="2"><nlm:affiliation>Lurie Children's Hospital of Chicago, Chicago, Illinois.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Lurie Children's Hospital of Chicago, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Moore, Jeffrey" sort="Moore, Jeffrey" uniqKey="Moore J" first="Jeffrey" last="Moore">Jeffrey Moore</name><affiliation><nlm:affiliation>University of Michigan, Ann Arbor.</nlm:affiliation><wicri:noCountry code="subField">Ann Arbor</wicri:noCountry></affiliation></author><author><name sortKey="Sherker, Averell H" sort="Sherker, Averell H" uniqKey="Sherker A" first="Averell H" last="Sherker">Averell H. Sherker</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Robuck, Patricia R" sort="Robuck, Patricia R" uniqKey="Robuck P" first="Patricia R" last="Robuck">Patricia R. Robuck</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Sokol, Ronald J" sort="Sokol, Ronald J" uniqKey="Sokol R" first="Ronald J" last="Sokol">Ronald J. Sokol</name><affiliation><nlm:affiliation>University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.</nlm:affiliation><wicri:noCountry code="subField">Aurora</wicri:noCountry></affiliation></author></analytic><series><title level="j">JAMA</title><idno type="eISSN">1538-3598</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Oral</term><term>Adrenal Cortex Hormones (administration & dosage)</term><term>Adrenal Cortex Hormones (adverse effects)</term><term>Biliary Atresia (drug therapy)</term><term>Biliary Atresia (surgery)</term><term>Bilirubin (blood)</term><term>Double-Blind Method</term><term>Drainage (methods)</term><term>Female</term><term>Humans</term><term>Infant</term><term>Infusions, Intravenous</term><term>Male</term><term>Methylprednisolone (administration & dosage)</term><term>Methylprednisolone (adverse effects)</term><term>Portoenterostomy, Hepatic</term><term>Prednisolone (administration & dosage)</term><term>Prednisolone (adverse effects)</term><term>Survival Analysis</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Administration par voie orale</term><term>Analyse de survie</term><term>Atrésie des voies biliaires ()</term><term>Atrésie des voies biliaires (traitement médicamenteux)</term><term>Bilirubine (sang)</term><term>Drainage ()</term><term>Femelle</term><term>Hormones corticosurrénaliennes (administration et posologie)</term><term>Hormones corticosurrénaliennes (effets indésirables)</term><term>Humains</term><term>Hépato-porto-entérostomie</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Méthylprednisolone (administration et posologie)</term><term>Méthylprednisolone (effets indésirables)</term><term>Nourrisson</term><term>Perfusions veineuses</term><term>Prednisolone (administration et posologie)</term><term>Prednisolone (effets indésirables)</term><term>Résultat thérapeutique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Adrenal Cortex Hormones</term><term>Methylprednisolone</term><term>Prednisolone</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Adrenal Cortex Hormones</term><term>Methylprednisolone</term><term>Prednisolone</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Bilirubin</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Hormones corticosurrénaliennes</term><term>Méthylprednisolone</term><term>Prednisolone</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Biliary Atresia</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Hormones corticosurrénaliennes</term><term>Méthylprednisolone</term><term>Prednisolone</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Drainage</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Bilirubine</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Biliary Atresia</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Atrésie des voies biliaires</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Infant</term><term>Infusions, Intravenous</term><term>Male</term><term>Portoenterostomy, Hepatic</term><term>Survival Analysis</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie orale</term><term>Analyse de survie</term><term>Atrésie des voies biliaires</term><term>Drainage</term><term>Femelle</term><term>Humains</term><term>Hépato-porto-entérostomie</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nourrisson</term><term>Perfusions veineuses</term><term>Résultat thérapeutique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Biliary atresia is the most common cause of end-stage liver disease in children. Controversy exists as to whether use of steroids after hepatoportoenterostomy improves clinical outcome.</div></front></TEI><affiliations><list><country><li>Géorgie (pays)</li><li>États-Unis</li></country><region><li>Californie</li><li>Illinois</li><li>Maryland</li><li>Missouri (État)</li><li>Ohio</li><li>Pennsylvanie</li><li>Texas</li><li>Washington (État)</li></region><settlement><li>Houston</li><li>Los Angeles</li></settlement></list><tree><noCountry><name sortKey="Magee, John C" sort="Magee, John C" uniqKey="Magee J" first="John C" last="Magee">John C. Magee</name><name sortKey="Molleston, Jean P" sort="Molleston, Jean P" uniqKey="Molleston J" first="Jean P" last="Molleston">Jean P. Molleston</name><name sortKey="Moore, Jeffrey" sort="Moore, Jeffrey" uniqKey="Moore J" first="Jeffrey" last="Moore">Jeffrey Moore</name><name sortKey="Sokol, Ronald J" sort="Sokol, Ronald J" uniqKey="Sokol R" first="Ronald J" last="Sokol">Ronald J. Sokol</name><name sortKey="Spino, Cathie" sort="Spino, Cathie" uniqKey="Spino C" first="Cathie" last="Spino">Cathie Spino</name><name sortKey="Suchy, Frederick J" sort="Suchy, Frederick J" uniqKey="Suchy F" first="Frederick J" last="Suchy">Frederick J. Suchy</name></noCountry><country name="États-Unis"><region name="Ohio"><name sortKey="Bezerra, Jorge A" sort="Bezerra, Jorge A" uniqKey="Bezerra J" first="Jorge A" last="Bezerra">Jorge A. Bezerra</name></region><name sortKey="Erlichman, Jessi" sort="Erlichman, Jessi" uniqKey="Erlichman J" first="Jessi" last="Erlichman">Jessi Erlichman</name><name sortKey="Haber, Barbara" sort="Haber, Barbara" uniqKey="Haber B" first="Barbara" last="Haber">Barbara Haber</name><name sortKey="Hertel, Paula M" sort="Hertel, Paula M" uniqKey="Hertel P" first="Paula M" last="Hertel">Paula M. Hertel</name><name sortKey="Kerkar, Nanda" sort="Kerkar, Nanda" uniqKey="Kerkar N" first="Nanda" last="Kerkar">Nanda Kerkar</name><name sortKey="Loomes, Kathleen M" sort="Loomes, Kathleen M" uniqKey="Loomes K" first="Kathleen M" last="Loomes">Kathleen M. Loomes</name><name sortKey="Murray, Karen F" sort="Murray, Karen F" uniqKey="Murray K" first="Karen F" last="Murray">Karen F. Murray</name><name sortKey="Robuck, Patricia R" sort="Robuck, Patricia R" uniqKey="Robuck P" first="Patricia R" last="Robuck">Patricia R. Robuck</name><name sortKey="Rosenthal, Philip" sort="Rosenthal, Philip" uniqKey="Rosenthal P" first="Philip" last="Rosenthal">Philip Rosenthal</name><name sortKey="Schwarz, Kathleen B" sort="Schwarz, Kathleen B" uniqKey="Schwarz K" first="Kathleen B" last="Schwarz">Kathleen B. Schwarz</name><name sortKey="Shepherd, Ross" sort="Shepherd, Ross" uniqKey="Shepherd R" first="Ross" last="Shepherd">Ross Shepherd</name><name sortKey="Sherker, Averell H" sort="Sherker, Averell H" uniqKey="Sherker A" first="Averell H" last="Sherker">Averell H. Sherker</name><name sortKey="Shneider, Benjamin L" sort="Shneider, Benjamin L" uniqKey="Shneider B" first="Benjamin L" last="Shneider">Benjamin L. Shneider</name><name sortKey="Turmelle, Yumirle P" sort="Turmelle, Yumirle P" uniqKey="Turmelle Y" first="Yumirle P" last="Turmelle">Yumirle P. Turmelle</name><name sortKey="Wang, Kasper S" sort="Wang, Kasper S" uniqKey="Wang K" first="Kasper S" last="Wang">Kasper S. Wang</name><name sortKey="Whitington, Peter F" sort="Whitington, Peter F" uniqKey="Whitington P" first="Peter F" last="Whitington">Peter F. Whitington</name></country><country name="Géorgie (pays)"><noRegion><name sortKey="Karpen, Saul J" sort="Karpen, Saul J" uniqKey="Karpen S" first="Saul J" last="Karpen">Saul J. Karpen</name></noRegion><name sortKey="Romero, Rene" sort="Romero, Rene" uniqKey="Romero R" first="Rene" last="Romero">Rene Romero</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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